Dr Takayoshi Ubuka

Contact Details

Tel: +603 5514 6374
Fax: +603 5514 6341
Office: Room 3-3-05
Email: takayoshi.ubuka@monash.edu

Profile Summary

Dr Takayoshi Ubuka undertook his doctorate in Biosphere Science at Hiroshima University in 2005. He then attended the University of California, Berkeley until 2010 for his postdoctoral studies. Ubuka was a Research Fellow in Brain Science at Waseda University and Lecturer in Biology at Tokyo Medical and Dental University before he joined BRIMS in 2015. He is a member of American Chemical Society, International Congress of Comparative Endocrinology, Asia and Oceania Society for Comparative Endocrinology, International Symposium on Avian Endocrinology (International Council Member), and sub-committee member of International Union of Basic and Clinical Pharmacology (IUPHAR) Database, G protein-coupled receptors, Neuropeptide FF/neuropeptide AF receptors section. He was awarded the Excellence in Reviewing Award from General and Comparative Endocrinology in 2013.

Qualifications

MSci (Hiroshima), PhD (Hiroshima)

Research Interests

Dr Takayoshi Ubuka is interested in the mechanism of how hormones and environmental factors shape the neuronal architecture and regulate instinctive behavior, especially the social behavior. He wishes to identify the risk factors for autism spectrum disorder, which is a neurodevelopmental disorder, characterized by impaired social interaction, verbal and non-verbal communication, and restricted and repetitive behavior by epidemiological studies as well as experiments using model animals.

Publications

Original research papers

  1. T. Ubuka and K. Tsutsui. Evolution of gonadotropin-inhibitory hormone receptor and its ligand. Gen. Comp. Endocrinol. 209, 148–161 (2014).
  2. N. T. Ashley, T. Ubuka, I. Schwabl, W. Goymann, B. M. Salli, G. E. Bentley, and C. L. Buck. Constant illumination alters optic per2 expression, plasma melatonin, and locomotory activity in arctic-breeding songbirds, Lapland longspurs (Calcarius lapponicus). J. Biol. Rhythms. 29, 456–469 (2014).
  3. B. McConn, G. Wang, J. Yi, E. Gilbert, T. Osugi, T. Ubuka, K. Tsutsui, V. Chowdhury, M. Furuse, and M. Cline. Gonadotropin-inhibitory hormone-stimulation of food intake is mediated by hypothalamic effects in chicks. Neuropeptides 48, 327–334 (2014).
  4. Y. Tobari, Y. L. Son, T. Ubuka, Y. Hasegawa, and K. Tsutsui. A new pathway mediating social effects on the endocrine system: female presence acting via norepinephrine release stimulates gonadotropin-inhibitory hormone in the paraventricular nucleus and suppresses luteinizing hormone in quail. J. Neurosci. 34, 9803–9811 (2014).
  5. T. Osugi, T. Okamura, Y. L. Son, M. Ohkubo, T. Ubuka, Y. Henmi, and K. Tsutsui. Evolutionary origin of GnIH and NPFF in chordates: insights from novel amphioxus RFamide peptides. PLoS One 9, e100962 (2014).
  6. Y. L. Son, T. Ubuka, M. Narihiro, Y. Fukuda, I. Hasunuma, K. Yamamoto, D. D. Belsham, and K. Tsutsui. Molecular basis for the activation of gonadotropin-inhibitory hormone gene transcription by corticosterone. Endocrinology 155, 1817–1826 (2014).
  7. T. Ubuka, S. Haraguchi, Y. Tobari, M. Narihiro, K. Ishikawa, T. Hayashi, N. Harada, and K. Tsutsui. Hypothalamic inhibition of socio-sexual behaviors by increasing neuroestrogen synthesis. Nat. Commun. 5, 3061 (2014).
  8. S. Haraguchi, S. Hara, T. Ubuka, M. Mita, and K. Tsutsui. Possible role of pineal allopregnanolone in Purkinje cell survival. Proc. Natl. Acad. Sci. USA. 109, 21110–21115 (2012).
  9. T. Osugi, D. Daukss, K. Gazda, T. Ubuka, T. Kosugi, S. A. Sower, and K. Tsutsui. Evolutionary origin of the structure and function of gonadotropin-inhibitory hormone: Insights from lampreys. Endocrinology 153, 2362–2374 (2012).
  10. Y. L. Son, T. Ubuka, R. P. Millar, and K. Tsutsui. Gonadotropin-inhibitory hormone inhibits GnRH-I induced gonadotropin subunit gene transcriptions by inhibiting AC/cAMP/PKA-dependent ERK pathway in LβT2 cells. Endocrinology 153, 2332–2343 (2012).
  11. N. Treen, N. Itoh, H. Miura, I. Kikuchi, T. Ueda, K. G. Takahashi, T. Ubuka, K. Yamamoto, P. J. Sharp, K. Tsutsui, and M. Osada. Mollusc gonadotropin-releasing hormone directly regulates gonadal functions: A primitive endocrine system controlling reproduction. Gen. Comp. Endocrinol. 176, 167–172 (2012).
  12. S. Haraguchi, T. Koyama, I. Hasunuma, S. Okuyama, T. Ubuka, S. Kikuyama, J. L. Do Rego, H. Vaudry, and K. Tsutsui. Acute stress increases the synthesis of 7α-hydroxypregnenolone, a new key neurosteroid stimulating locomotor activity, through corticosterone action in newts. Endocrinology 153, 794–805 (2012).
  13. T. Ubuka, K. Inoue, Y. Fukuda, T. Mizuno, K. Ukena, L. J. Kriegsfeld, and K. Tsutsui. Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone. Endocrinology 153, 373–385 (2012).
  14. T. Ubuka, M. Mukai, J. Wolfe, R. Beverly, S. Clegg, A. Wang, S. Hsia, M. Li, J. S. Krause, T. Mizuno, Y. Fukuda, K. Tsutsui, G. E. Bentley, and J. C. Wingfield. RNA interference of gonadotropin-inhibitory hormone gene induces arousal in songbirds. PLoS One 7, e30202 (2012).
  15. Y. Tobari, N. Iijima, K. Tsunekawa, T. Osugi, S. Haraguchi, T. Ubuka, K. Ukena, K. Okanoya, K. Tsutsui, and H. Ozawa. Identification, localization and functional implication of 26RFa ortholog peptide in the brain of zebra finch (Taeniopygia guttata). J. Neuroendocrinol. 23, 791–803 (2011).
  16. N. Perfito, R. Zann, T. Ubuka, G. E. Bentley, and M. Hau. Potential roles for GNIH and GNRH-II in reproductive axis regulation of an opportunistically breeding songbird. Gen. Comp. Endocrinol. 173, 20–26 (2011).
  17. V. S. Chowdhury, T. Ubuka, T. Osugi, T. Shimura, and K. Tsutsui. Identification, localization and expression of LPXRFamide peptides, and melatonin-dependent induction of their precursor mRNA in the newt brain. J. Endocrinol. 209, 211–220 (2011).
  18. A. O. Mason, S. Duffy, S. Zhao, T. Ubuka, G. E. Bentley, K. Tsutsui, R. Silver, and L. J. Kriegsfeld. Photoperiod and reproductive condition are associated with changes in RFamide-related peptide (RFRP) expression in Syrian hamsters (Mesocricetus auratus). J. Biol. Rhythms 25, 176–185 (2010).
  19. V. S. Chowdhury, K. Yamamoto, T. Ubuka, G. E. Bentley, A. Hattori, and K. Tsutsui. Melatonin stimulates the release of gonadotropin-inhibitory hormone by the avian hypothalamus. Endocrinology 151, 271–280 (2010).
  20. T. Ubuka, K. Morgan, A. J. Pawson, T. Osugi, V. S. Chowdhury, H. Minakata, K. Tsutsui, R. P. Millar, and G. E. Bentley. Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. PLoS One 4, e8400 (2009).
  21. T. Ubuka, H. Lai, M. Kitani, A. Suzuuchi, V. Pham, P. A. Cadigan, A. Wang, V. S. Chowdhury, K. Tsutsui, and G. E. Bentley. Gonadotropin-inhibitory hormone identification, cDNA cloning and distribution in rhesus macaque brain. J. Comp. Neurol. 517, 841–855 (2009).
  22. E. D. Kirby, A. C. Geraghty, T. Ubuka, G. E. Bentley, and K. Daniela. Stress increases putative gonadotropin inhibitory hormone and decreases luteinizing hormone in male rats. Proc. Natl. Acad. Sci. USA. 106, 11324–11329 (2009).
  23. T. Ubuka, P. A. Cadigan, A. Wang, J. Liu, and G. E. Bentley. Identification of European starling GnRH-I precursor mRNA and its seasonal regulation. Gen. Comp. Endocrinol. 162, 301–306 (2009).
  24. T. Ubuka and G. E. Bentley. Identification, localization and regulation of passerine gonadotropin- releasing hormone-I messenger RNA. J. Endocrinol. 201, 81–87 (2009).
  25. I. J. Clarke, I. P. Sari, Y. Qi, J. T. Smith, H. C. Parkington, T. Ubuka, J. Iqbal, Q. Li, A. Tilbrook, K. Morgan, A. J. Pawson, K. Tsutsui, R. P. Millar, and G. E. Bentley. Potent action of RFRP-3 on pituitary gonadotropes indicative of an hypophysiotropic role in the negative regulation of gonadotropin secretion. Endocrinology 149, 5811–5821 (2008).
  26. J. T. Smith, L. M. Coolen, L. J. Kriegsfeld, I. P. Sari, M. R. Jaafarzadehshirazi, M. Maltby, K. Bateman, R. L. Goodman, A. J. Tilbrook, T. Ubuka, G. E. Bentley, I. J. Clarke, and M. N. Lehman. Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep. Endocrinology 149, 5770–5782 (2008).
  27. T. J. Stevenson, G. E. Bentley, T. Ubuka, L. Arckens, E. Hampson, and S. A. MacDougall-Shackleton. Effects of social cues on GnRH-I, GnRH-II, and reproductive physiology in female house sparrows (Passer domesticus). Gen. Comp. Endocrinol. 156, 385–394 (2008).
  28. G. E. Bentley, T. Ubuka, N. L. McGuire, V. S. Chowdhury, Y. Morita, T. Yano, I. Hasunuma, M. Binns, J. C. Wingfield, and K. Tsutsui. Gonadotropin-inhibitory hormone and its receptor in the avian reproductive system. Gen. Comp. Endocrinol. 156, 34–43 (2008).
  29. T. Ubuka, S. Kim, Y. C. Huang, J. Reid, J. Jiang, T. Osugi, V. S. Chowdhury, K. Tsutsui, and G. E. Bentley. Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-releasing hormone-I and -II neurons in European starling brain. Endocrinology 149, 268–278 (2008).
  30. T. Ubuka, K. Ukena, P. J. Sharp, G. E. Bentley, and K. Tsutsui. Gonadotropin-inhibitory hormone inhibits gonadal development and maintenance by decreasing gonadotropin synthesis and release in male quail. Endocrinology 147, 1187–1194 (2006).
  31. L. Kriegsfeld, D. F. Mei, G. E. Bentley, T. Ubuka, A. O. Manson, K. Inoue, K. Ukena, K. Tsutsui, and R. Silver. Identification and characterization of a gonadotropin-inhibitory system in the brain of mammals. Proc. Natl. Acad. Sci. USA. 103, 2410–2415 (2006).
  32. T. Ubuka, G. E. Bentley, K. Ukena, J. C. Wingfield, and K. Tsutsui. Melatonin induces the expression of gonadotropin-inhibitory hormone. Proc. Natl. Acad. Sci. USA. 102, 3052–3057 (2005).
  33. H. Yin, K. Ukena, T. Ubuka, and Tsutsui K. A novel G protein-coupled receptor for gonadotropin-inhibitory hormone in the Japanese quail (Coturnix japonica): identification, expression and binding activity. J. Endocrinol. 184, 257–266 (2005).
  34. N. A. Ciccone, I. C. Dunn, T. Boswell, K. Tsutsui, T. Ubuka, K. Ukena, and P. J. Sharp. Gonadotrophin inhibitory hormone depresses gonadotrophin α and follicle-stimulating hormone β subunit expression in the pituitary of the domestic chicken. J. Neuroendocrinol. 16, 999–1006 (2004).
  35. Y. Haida, T. Ubuka, K. Ukena, K. Tsutsui, T. Oishi, and S. Tamotsu. Photoperiodic response of serotonin- and galanin-immunoreactive neurons of the paraventricular organ and infundibular nucleus in Japanese quail, Coturnix coturnix japonica. Zool. Sci. 21, 575–582 (2004).
  36. T. Ubuka, M. Ueno, K. Ukena, and K. Tsutsui. Developmental changes in gonadotropin-inhibitory hormone in the Japanese quail (Coturnix japonica) hypothalamo-hypophysial system. J. Endocrinol. 178, 311–318 (2003).
  37. K. Ukena, T. Ubuka, and K. Tsutsui. Distribution of a novel avian gonadotropin-inhibitory hormone in the quail brain. Cell. Tissue Res. 312, 73–79 (2003).
  38. T. Ubuka, H. Sakamoto, D. Li, K. Ukena, and K. Tsutsui. Developmental changes in galanin in lumbosacral sympathetic ganglionic neurons innervating the avian uterine oviduct and galanin induction by sex steroids. J. Endocrinol. 170, 357–368 (2001).
  39. H. Sakamoto, T. Ubuka, C. Kohchi, D. Li, K. Ukena, and K. Tsutsui. Existence of galanin in lumbosacral sympathetic ganglionic neurons that project to the quail uterine oviduct. Endocrinology 141, 4402–4412 (2000).


Review papers

  1. Ubuka T et al. Molecular, cellular, morphological, physiological and behavioral aspects of gonadotropin-inhibitory hormone. Gen. Comp. Endocrinol. 2016. 227: 27-50.
  2. J. C. Wingfield, N. Perfito, R. Calisi, G. E. Bentley, T. Ubuka, M. Mukai, S. O'Brien, and K. Tsutsui. Putting the brakes on reproduction: Implications for conservation, global climate change and biomedicine. Gen. Comp. Endocrinol. In press. (2015). doi: 10.1016/j.ygcen.2015.10.007.
  3. T. Osugi, Y. L. Son, T. Ubuka, H. Satake, and K. Tsutsui. RFamide peptides in agnathans and basal chordates. Gen. Comp. Endocrinol. In press. (2015).
  4. T. Ubuka. Neuropeptide regulation of neurosteroid synthesis. New endocrinological phenomena. Comparative Endocrinology 41, 3–7 (2015). Japanese
  5. L. J. Kriegsfeld, T. Ubuka, G. E. Bentley, and K. Tsutsui. Seasonal control of gonadotropin-inhibitory hormone (GnIH) in birds and mammals. Front. Neuroendocrinol. 37, 65–75 (2015).
  6. K. Tsutsui, T. Ubuka, Y.L. Son, G.E. Bentley, and L.J. Kriegsfeld. Contribution of GnIH Research to the Progress of Reproductive Neuroendocrinology. Front. Endocrinol (Lausanne). 6, 179 (2015).
  7. T. Osugi, T. Ubuka, and K. Tsutsui. An evolutionary scenario for gonadotrophin-inhibitory hormone in chordates. J. Neuroendocrinol. 27, 556–566 (2015).
  8. T. Ubuka and K. Tsutsui. Neuroestrogen regulation of socio-sexual behavior of males. Front. Neurosci. 8, 323 (2014).
  9. T. Ubuka and K. Tsutsui. Gonadotropin-inhibitory hormone (GnIH) inhibits aggressive behavior of male quail by increasing neuroestrogen synthesis. Japanese Journal of Reproductive Endocrinology 19, 57–59 (2014). Japanese
  10. T. Osugi, T. Ubuka, and K. Tsutsui. Review: evolution of GnIH and related peptides structure and function in the chordates. Front. Neurosci. 8, 255 (2014).
  11. T. Ubuka and K. Tsutsui. Gonadotropin-inhibitory hormone inhibits aggressive behavior of male quail by increasing neuroestrogen synthesis in the brain beyond its optimum concentration. Gen. Comp. Endocrinol. 205C, 49–54 (2014).
  12. T. Ubuka, Y. L. Son, Y. Tobari, M. Narihiro, G. E. Bentley, L. J. Kriegsfeld, and K. Tsutsui. Central and direct regulation of testicular activity by gonadotropin-inhibitory hormone and its receptor. Front. Endocrinol. (Lausanne). 5, 8 (2014).
  13. T. Ubuka, Y. L. Son, G. E. Bentley, R. P. Millar, and K. Tsutsui. Gonadotropin-inhibitory hormone (GnIH), GnIH receptor and cell signaling. Gen. Comp. Endocrinol. 190, 10–17 (2013).
  14. T. Ubuka, K. Inoue, and K. Tsutsui. Identification of hamster GnIH and analyses of its regulatory mechanism and physiological function. Japanese Journal of Reproductive Endocrinology 18, 27–33 (2013). Japanese
  15. T. Ubuka, T. Mizuno, Y. Fukuda, G. E. Bentley, J. C. Wingfield, and K. Tsutsui. RNA interference of gonadotropin-inhibitory hormone gene induces aggressive and sexual behaviors in birds. Gen. Comp. Endocrinol. 181, 179–186 (2012).
  16. V. S. Chowdhury, T. Ubuka, and K. Tsutsui. Review: Melatonin stimulates the synthesis and release of gonadotropin-inhibitory hormone in birds. Gen. Comp. Endocrinol. 181, 175–178 (2013).
  17. K. Tsutsui, T. Ubuka, G. E. Bentley, and L. J. Kriegsfeld. Review: regulatory mechanisms of gonadotropin-inhibitory hormone (GnIH) synthesis and release in photoperiodic animals. Front. Neurosci. 7, 60 (2013).
  18. T. Ubuka, G. E. Bentley, and K. Tsutsui. Neuroendocrine regulation of gonadotropin secretion in seasonally breeding birds. Front. Neurosci. 7, 38 (2013).
  19. K. Tsutsui, T. Ubuka, G. E. Bentley, and L. J. Kriegsfeld. Gonadotropin-inhibitory hormone (GnIH): discovery, progress and prospect. Gen. Comp. Endocrinol. 177, 305–314 (2012).
  20. T. Ubuka, Y. L. Son, Y. Tobari, and K. Tsutsui. Gonadotropin-inhibitory hormone action in the brain and pituitary. Front. Endocrinol. (Lausanne) 3, 148 (2012).
  21. K. Tsutsui, T. Osugi, Y. Tobari, Y. L. Son, and T. Ubuka. The origin and evolution of a novel brain hormone, gonadotropin-inhibitory hormone (GnIH). Comparative Endocrinology 38, 76–82 (2012). Japanese
  22. K. Tsutsui, G. E. Bentley, G. Bedecarrats, T. Osugi, T. Ubuka, and L. J. Kriegsfeld. Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function. Front. Neuroendocrinol. 31, 284–295 (2010).
  23. K. Tsutsui and T. Ubuka. Reproductive cycle and neuropeptide. (2) GnIH. Hormone Frontier in Gynecology 17, 25–29 (2010). Japanese
  24. G. E. Bentley, T. Ubuka, N. L. McGuire, R. Calisi, N. Perfito, L. J. Kriegsfeld, J. C. Wingfield, and K. Tsutsui. Gonadotrophin-inhibitory hormone: a multifunctional neuropeptide. J. Neuroendocrinol. 21, 276–281 (2009).
  25. K. Tsutsui, E. Saigoh, H. Yin, T. Ubuka, V. S. Chowdhury, T. Osugi, K. Ukena, P. J. Sharp, J. C. Wingfield, and G. E. Bentley. A new key neurohormone controlling reproduction, gonadotrophin-inhibitory hormone in birds: discovery, progress and prospects. J. Neuroendocrinol. 21, 271–275 (2009).
  26. T. Ubuka, N. L. McGuire, R. M. Calisi, N. Perfito, and G. E. Bentley. The control of reproductive physiology and behavior by gonadotropin-inhibitory hormone. Integr. Comp. Biol. 48, 560–569 (2008).
  27. K. Tsutsui, G. E. Bentley, T. Ubuka, E. Saigoh, H. Yin, T. Osugi, K. Inoue, V. S. Chowdhury, K. Ukena, N. Ciccone, P. J. Sharp, and J. C. Wingfield. The general and comparative biology of gonadotropin-inhibitory hormone (GnIH). Gen. Comp. Endocrinol. 153, 365−370 (2007).
  28. K. Tsutsui, T. Ubuka, H. Yin, T. Osugi, K. Ukena, G. E. Bentley, N. Ciccone, K. Inoue, V. S. Chowdhury, P. J. Sharp, and J. C. Wingfield. Mode of action and functional significance of avian gonadotropin-inhibitory hormone (GnIH): A review. J. Exp. Zool. A Comp. Exp. Biol. 305, 801–806 (2006).


Book chapters

  1. K. Tsutsui and T. Ubuka. RFamide peptide family. In: Takei Y., Ando H., Tsutsui K. eds. Handbook on Hormones: Comparative Endocrinology for Basic and Clinical Research. Part 1. Peptides and proteins in vertebrates, Section 1.1. Neuropeptides. Elsevier B.V., pp. 5-6, e1-1-e1-2 (2015).
  2. K. Tsutsui and T. Ubuka. Gonadotropin-inhibitory hormone. In: Takei Y., Ando H., Tsutsui K. eds. Handbook on Hormones: Comparative Endocrinology for Basic and Clinical Research. Part 1. Peptides and proteins in vertebrates, Section 1.1. Neuropeptides. Elsevier B.V., pp. 7-9, e1A-1-e1A-2 (2015).
  3. T. Osugi, T. Ubuka and K. Tsutsui. PQRFamide peptide. In: Takei Y., Ando H., Tsutsui K. eds. Handbook on Hormones: Comparative Endocrinology for Basic and Clinical Research. Part 1. Peptides and proteins in vertebrates, Section 1.1. Neuropeptides. Elsevier B.V., pp. 13-15, e1C-2-e1C-3 (2015).
  4. T. Ubuka and G. E. Bentley. Avian gonadotropin-releasing hormone (GnRH): Structure, function and regulation. In: Sills S. ed. Gonadotropin-Releasing Hormone (GnRH): Production, Structure & Function. Nova Science Publishers Inc., New York, pp. 69–83 (2013).
  5. K. Tsutsui and T. Ubuka. Gonadotropin-inhibitory Hormone. In: Kastin A. J. and Vaudry H. eds. Handbook of biologically active peptides. Section on brain peptides. Academic Press, London, pp. 802–811 (2012).
  6. T. Ubuka and G. E. Bentley. Neuroendocrine control of reproduction in birds. In: Norris D. O. and Lopez K. H. eds. Hormones and Reproduction of Vertebrates Vol 4. Birds. Academic Press, London, pp. 1–25. (2010).
  7. K. Tsutsui, T. Ubuka, and G. E. Bentley. Melatonin action on neuropeptide induction through receptor-mediated mechanisms in the brain. In: Cardinali, D. P. and Pandi-Perumal, S. R. eds. MELATONIN from Molecules to Therapy, I. Molecular Perspectives. Nova Science Publishers Inc., New York, pp. 387–400 (2006).
  8. H. Sakamoto, T. Ubuka, C. Kohchi, K. Ukena, and K. Tsutsui. Sympathetic ganglionic galanin neurons evoke avian oviposition by innervating the uterine oviduct: A novel neuronal mechanism of avian oviposition. In: H. J. Th. Goos et al. eds. Perspective in Comparative Endocrinology. Monduzzi Editore, Bologna, pp. 647–653 (2001).


Proceedings

  1. K. Tsutsui and T. Ubuka. Breakthrough in neuroendocrinology by discovering novel neuropeptides and neurosteroids: 1) Discovery of gonadotropin-inhibitory hormone (GnIH) across vertebrates. Bargmann-Scharrer Lecture at the 17th International Congress of Comparative Endocrinology (2013). Gen. Comp. Endocrinol. 205C, 4-10.
  2. K. Tsutsui, S. Haraguchi, K. Inoue, H. Miyabara, S. Suzuki, and T. Ubuka. Control of circadian activity of birds by the interaction of melatonin with 7α-hydroxypregnenolone, a newly discovered neurosteroid stimulating locomotion. Proceedings of the 25th International Ornithological Congress (2010). J. Ornithol. 153, S 235–S243 (2011).
  3. G. E. Bentley, N. Perfito, T. Ubuka, K. Ukena, T. Osugi, S. O’Brien, K. Tsutsui, and J. C. Wingfield. Gonadotropin-inhibitory hormone in seasonally-breeding songbirds: neuroanatomy and functional biology. Proceedings of the 24th International Ornithological Congress (2006). J. Ornithol. 148, S521–S526 (2007).
  4. K. Tsutsui, T. Ubuka, H. Yin, T. Osugi, K. Ukena, G. E. Bentley, P. J. Sharp, and J. C. Wingfield. Discovery of gonadotropin-inhibitory hormone in a domesticated bird, and its mode of action and functional significance. Proceedings of the 24th International Ornithological Congress (2006). J. Ornithol.148, S515–S520 (2007).